Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Galectin-1 Antagonist, DB21
A dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3
MilliporeSigma™ Calbiochem™ GSK-3beta Inhibitor XXVII, CESI
A cell-permeable, 3-hydroxychromone derived compound that acts as a selective and reversible inhibitor of GSK-3β (IC50 < 100
MilliporeSigma™ Calbiochem™ Plasminogen Activator Inhibitor-1, Mutant, Mouse, Recombinant
The Plasminogen Activator Inhibitor-1, Mutant, Mouse, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ L-Serine-O-phosphate
A potent agonist for group III mGlu receptor subtype 4, 6, and 8.
MilliporeSigma™ Calbiochem™ p53 Modulator, CP-31398
A cell-permeable styrylquinazoline compound that protects wild-type p53 against heat-induced denaturation and locks newly synthesized mutant p53 in an active conformation.
MilliporeSigma™ Calbiochem™ Bax Activator, BAM7
The Bax Activator, BAM7 modulates the biological activity of Bax. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ 14-3-3 Antagonist II, BV02
The 14-3-3 Antagonist II, BV02 controls the biological activity of 14-3-3.
Novus Biologicals™ Etoposide Inhibitor
Low molecular weight, organic compound that may help regulate biological process.
Novus Biologicals™ MSC 2032964A Inhibitor
Low molecular weight, organic compound that may help regulate biological process.
MilliporeSigma™ Calbiochem™ G 418 Sulfate, Sterile-Filtered Solution in PBS, Cell Culture-Tested
The optimal concentration of G418 for selection of resistance will vary according to the organism and/or cell type under investigation
MilliporeSigma™ Calbiochem™ A-803467
A voltage gated sodium channel type 1.8 (Nav1.8) pore blocker. Potently blocks tetrodotoxin-resistant currents (IC50) = 140 nM).
MilliporeSigma™ Calbiochem™ PKM2 Activator III
A cell-permeable quinoline-sulfonamide that acts as a potent allosteric PKM2 activator both in cell-free enzymatic assays (AC50 = 17nM with 40 ng PKM2/200μL) and in cultures (AC50 = 45nM in A549 cells) via a high affinity, 2:1 stoichiometric binding, effectively locking PKM2 in an active tetrameric state resistant to known intracellular negative regulators of FBP-activated PKM2 te
MilliporeSigma™ Calbiochem™ O-1602
A potent agonist for the putative cannabinoid receptor, G protein-coupled receptor 55 (GPR55 receptor) (EC50 = 13)
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor IX, WP1193
A cell-permeable tyrphostin WP1130 (Cat
MilliporeSigma™ Calbiochem™ Aβ42 Fibrillogenesis Inhibitor III
Fibrillogenesis Inhibitor III controls the biological activity of Aβ42Fibrillogenesis. This small molecule/inhibitor is primarily used for Neuroscience applications.